Faculty of Science

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    Characterization and evaluation of repellent effect of essential oil of mangifera indica l. from Kenya
    (Journal of Essential Oil Bearing Plants, 2013-03-12) Alwala, J.O.; Wanzala, W.; Inyambukho, RA.
    Ethnopharmacologically, the mango has a lot of applications in life in humanhealth and ethnoveterinary medicines since ancient times. The study aimed at characterizing theessential oil of Mangifera indica L. leaves and evaluating its repellent effect on the host-seekingfemale Anopheles gambiae,the vector of African malaria. The essential oil was obtained byhydrodistillation and analyzed by gas chromatography (GC) and gas chromatography-massspectrometry (GC-MS). The repellent effect of the essential oil was evaluated using the human-baittechnique to simulate field situation. Of the 26 major hydrocarbon compounds identified, α-pineneoccurred in the largest amount (33.3 %), followed by α-phellandrene (22.6 %), Limonene (13.2 %),p-cymene (6.1 %), Heptane (3.8 %), β-pinene (2.6 %), Ledene (1.3 %), (-)-α-gurjunene (1.2 %), β-myrcene (1.1 %), γ-terpinene (1.0 %), (+)-2-carene (0.9 %) and trans (β)-caryophyllene (0.9 %) inthat order. The oil showed a significant dose-dependent repellent effect on host-seeking femaleAnopheles gambiae s.s. The oil showed a complex composition of hydrocarbon compounds andmay be richer in monoterpenes than in any other type of compounds. It showed the potential to repelmosquitoes.